Background Matinas BioPharma Holdings, Inc. (“Matinas” or the “Company”) is a clinical-stage biopharmaceutical company focused on delivering groundbreaking therapies using our lipid nanocrystal (“LNC”) platform delivery technology (the “LNC Platform”). Our lead product candidate is MAT2203 (oral amphotericin B), a highly potent antifungal drug which, by virtue of LNC delivery, has been made oral, safe, and well-tolerated for prolonged administration in patients with life-threatening invasive fungal infections.
Partnerships Rutgers University: license agreement for LNC technology
Indications
Cryptococcal meningitis(Phase 2)
Invasive aspergillosis (patients with limited treatment options)(Phase 3)
Status note EnACT Phase 2 in cryptococcal meningitis completed; positioned for single Phase 3 registration trial (ORALTO) for invasive aspergillosis in patients with limited treatment options. Clinical development paused following Oct 2024 workforce reduction (80%); pursuing licensing, sale or other transaction; R&D expense $0 in H1 2026. Jul 2026 agreements contemplated selling Nanotechnologies (owner of MAT2203) and combining with GH Power; closing not assured.
Per-asset detail extracted from the 10-Q filed 2026-08-13. Fields the filing does not state are marked "not disclosed" rather than filled from other sources.
No lead program on file for this company.
No active ClinicalTrials.gov trials matched to this company as sponsor or collaborator.
Specialist fund holders
Tracked specialist funds: ADAR1 Capital Management, Aisling Capital, Ally Bridge Group, Avoro Capital Advisors, BVF Partners, Baker Bros. Advisors, Boxer Capital, Braidwell LP, Casdin Capital, Cormorant Asset Management, DAFNA Capital, Deerfield Management, EcoR1 Capital, Frazier Life Sciences, Great Point Partners, Ikarian Capital, Logos Global Management, OrbiMed Advisors, Perceptive Advisors, RA Capital Management, RTW Investments, Sphera Biotech, Stonepine Capital, Tang Capital Partners, Vivo Capital.
None of the tracked specialist funds reported a position in the latest 13F snapshot.
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