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TSHA — Taysha Gene Therapies Inc.

TSHA (Taysha Gene Therapies Inc.) stock: $4.33, $1.41B market cap, $455.4M cash, $1.00B EV, $1.57B fully diluted market cap. Next expected readout: Mar-27. Lead program: TSHA-102 (Rett Syndrome), Phase 3. Data from Fully Diluted's biotech stocks database.

What they do

We are a clinical-stage biotechnology company focused on advancing AAV-based gene therapies for the treatment of severe monogenic diseases of the central nervous system, or CNS. Our lead clinical program TSHA-102 is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease.

Source: 10-K FY2025 via SEC EDGAR

Share price
$4.33
Market cap
$1,410.9M
Cash
$455.4M
Enterprise value
$1,004.8M

Balance sheet

Cash$455.4M
Debt$49.3M
Net cash$406.2M
Enterprise value$1,004.8M
Basic shares325.8M shares
Fully diluted shares362.5M shares
Fully diluted market cap$1,569.5M
Cash per share$1.40
Quarterly burn$40.4M
Cash runway11.3 quarters

Cash figures as of 2026-06-30. Database snapshot: 2026-11-07.

Share structure

Common
325.8M
Pre-funded warrants
—
Options
24.6M
RSUs
12.1M
Warrants
0.0M
Converts
0.0M
Conv preferred
0.0M
ESPP reserve
—
FDSO
362.5M

Cap table as of 2025-12-31.

Price history

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Next catalyst

TSHA-102 · Est. Apr 1, 2027 · half midpoint · guided in 8 wks

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